Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331916 | 0.95 | SMPD1 (0.33) | GRM4SMPD1 | |
| SCHEMBL3280792 | 0.95 | GRM4 (0.35) | GRM4SMPD1 | |
| SCHEMBL3278260 | 0.93 | GRM4 (0.34) | GRM4SMPD1 | |
| SCHEMBL3283396 | 0.90 | SMPD1 (0.35) | GRM4SMPD1 | |
| SCHEMBL3280101 | 0.86 | SMPD1 (0.32) | GRM4SMPD1 | |
| SCHEMBL3279603 | 0.82 | GRM4 (0.32) | GRM4SMPD1 | |
| SCHEMBL7631051 | 0.80 | GRM4 (0.32) | GRM4SMPD1 | |
| SCHEMBL3283840 | 0.79 | SMPD1 (0.38) | GRM4SMPD1 | |
| SCHEMBL6260083 | 0.79 | SMPD1 (0.33) | GRM4SMPD1 | |
| SCHEMBL6352923 | 0.79 | SMPD1 (0.33) | GRM4SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326822-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030860-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |