Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.66 |
| ▸ | PPARG | P37231 | 18/20 | 0.66 |
| ▸ | PPARD | Q03181 | 16/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539210 | 0.93 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6484667 | 0.91 | PPARA (0.77) | PPARAPPARGPPARD | |
| SCHEMBL6484669 | 0.91 | PPARA (0.77) | PPARAPPARGPPARD | |
| SCHEMBL6484675 | 0.91 | PPARA (0.77) | PPARAPPARGPPARD | |
| SCHEMBL6493519 | 0.88 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL6493527 | 0.88 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL6493516 | 0.88 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL6493522 | 0.88 | PPARA (0.84) | PPARAPPARGPPARD | |
| SCHEMBL6482371 | 0.86 | PPARA (0.83) | PPARAPPARGPPARD | |
| SCHEMBL14544580 | 0.86 | PPARA (0.83) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555577-B1 | For treatment and/or prevention of conditions mediated by the Peroxisome Proliferator-Activated Receptors (PPAR), such as diabetes and/or obesity; 3-(4-(3-Biphenyl-4-yl-but-2-enyloxy)-phenyl)-2-butoxy-propionic acid for example | NOVO NORDISK A/S (DE) | 2003-04-29 | — | — | US | disclosed |