Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307278 | 0.84 | ELANE (0.58) | ELANE | |
| SCHEMBL7009038 | 0.83 | ELANE (0.53) | ELANE | |
| SCHEMBL7004780 | 0.80 | ELANE (0.66) | ELANE | |
| SCHEMBL7003649 | 0.79 | ELANE (0.52) | ELANE | |
| SCHEMBL9321332 | 0.74 | ELANE (0.49) | ELANE | |
| SCHEMBL9739193 | 0.73 | ELANE (0.49) | ELANE | |
| SCHEMBL7395544 | 0.73 | ELANE (0.46) | ELANE | |
| SCHEMBL7009044 | 0.72 | ELANE (0.63) | ELANE | |
| SCHEMBL7008337 | 0.71 | ELANE (0.50) | ELANE | |
| SCHEMBL7288144 | 0.70 | ELANE (0.60) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626378-B1 | Saccharin derivative proteolytic enzyme inhibitors | SANOFI SYNTHELABO (FR) | 2003-01-22 | — | — | EP | disclosed |
| US-5466701-A | Degenerative diseases | STERLING WINTHROP INC. (US) | 1995-11-14 | — | — | US | disclosed |
| US-5378720-A | Treatment of rheumatoid arthritis, emphysema, pancreatitis | STERLING WINTHROP INC. (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0626378-A1 | Saccharin derivative proteolytic enzyme inhibitors | STERLING WINTHROP INC. (US) | 1994-11-30 | — | — | EP | disclosed |