Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706302 | 0.77 | TLR7 (0.58) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL2706297 | 0.76 | TLR7 (0.58) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL2708373 | 0.74 | TLR7 (0.57) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL2707594 | 0.74 | TLR7 (0.61) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL5617005 | 0.73 | TLR7 (0.70) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL1486447 | 0.73 | TLR7 (0.53) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL6030934 | 0.72 | TLR7 (0.59) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL5748067 | 0.72 | TLR7 (0.53) | TLR7ADORA2ANUDT1PDE4DLMNA | |
| SCHEMBL3937093 | 0.72 | KDM4E (0.37) | TLR7LMNAADORA3 | |
| SCHEMBL22803659 | 0.71 | TLR7 (0.73) | TLR7ADORA2ANUDT1PDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341789-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002046189-A2 | ARYL ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |