Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162767 | 0.84 | KMT2A (0.69) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL3173912 | 0.82 | KMT2A (0.76) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL31588275 | 0.82 | KMT2A (0.76) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL5738792 | 0.80 | KMT2A (0.71) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL17870784 | 0.80 | KMT2A (1.00) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL5738787 | 0.80 | KMT2A (0.71) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL17870755 | 0.80 | KMT2A (1.00) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL5160622 | 0.79 | KMT2A (0.61) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL29072531 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1MEN1PBRM1GPR84 | |
| SCHEMBL7099040 | 0.78 | KMT2A (0.61) | KMT2AALDH1A1MEN1PBRM1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |