Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101004 | 0.86 | GNRHR (0.56) | GNRHRMEN1KMT2A | |
| SCHEMBL7007954 | 0.85 | GNRHR (1.00) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7494036 | 0.84 | GNRHR (0.99) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7496524 | 0.81 | GNRHR (0.91) | GNRHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7497722 | 0.80 | GNRHR (0.89) | GNRHRMEN1KMT2A | |
| SCHEMBL5076714 | 0.79 | GNRHR (0.88) | GNRHRMEN1KMT2A | |
| N-Benzylmethylamine SCHEMBL7750657 | 0.79 | GNRHR (0.63) | GNRHRMEN1KMT2A | |
| SCHEMBL7526343 | 0.79 | GNRHR (0.90) | GNRHRMEN1KMT2A | |
| SCHEMBL7521064 | 0.78 | GNRHR (0.73) | GNRHRMEN1KMT2A | |
| SCHEMBL7006144 | 0.78 | GNRHR (1.00) | GNRHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756599-B1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-11-26 | — | — | EP | claimed |