Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473373 | 0.82 | PTGES2 (0.61) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL6697828 | 0.82 | PTGES2 (0.60) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3473539 | 0.80 | PTGES2 (0.65) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3472654 | 0.79 | PTGES2 (0.64) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL16502999 | 0.79 | PTGES2 (0.64) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3472410 | 0.79 | PTGES2 (0.64) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL15690849 | 0.78 | PTGES2 (0.63) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3473873 | 0.78 | PTGES2 (0.63) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3474065 | 0.77 | PTGES2 (0.64) | PTGES2GAAL3MBTL1ALDH1A1POLB | |
| SCHEMBL3617632 | 0.76 | GAA (0.58) | PTGES2GAAL3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283831-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2003-02-19 | — | — | EP | claimed |
| WO-2001090090-A1 | INHIBITORS OF 11-BETA-HYDROXY STEROID DEHYDROGENASE TYPE 1 | BIOVITRUM AB (SE) | 2001-11-29 | — | — | WO | claimed |