SCHEMBL7097179

SCHEMBL7097179

CCSCc1cn(Cc2ccccc2F)c2sc(-c3ccc(OC)cc3)c(C(C)NCc3ccccc3)c2c1=O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GNRHR P30968 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7094025 0.89 GNRHR (0.53) GNRHR
SCHEMBL7098342 0.88 GNRHR (0.50) GNRHR
SCHEMBL7095739 0.87 GNRHR (0.49) GNRHR
SCHEMBL7097841 0.86 GNRHR (0.52) GNRHR
SCHEMBL7096825 0.83 GNRHR (0.51) GNRHR
SCHEMBL7007971 0.81 GNRHR (0.73) GNRHR
Hydrochloric Acid SCHEMBL7012329 0.80 GNRHR (0.72) GNRHR
SCHEMBL7254012 0.72 GNRHR (0.70) GNRHR
SCHEMBL8164276 0.71 GNRHR (0.60) GNRHR
N-Benzylmethylamine SCHEMBL7248204 0.71 GNRHR (0.76) GNRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0756599-B1 BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-11-26 EP claimed