⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20271689 | 1.00 | — | — | |
| SCHEMBL7542137 | 0.75 | — | — | |
| SCHEMBL6548466 | 0.75 | — | — | |
| SCHEMBL645473 | 0.73 | — | — | |
| SCHEMBL15438159 | 0.71 | — | — | |
| SCHEMBL17419781 | 0.71 | — | — | |
| SCHEMBL5384024 | 0.71 | PTPN7 (0.42) | — | |
| SCHEMBL3031858 | 0.71 | — | — | |
| SCHEMBL3031861 | 0.69 | — | — | |
| SCHEMBL1556126 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021493-B2 | 1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use | AMGEN INC. (US) | 2021-06-01 | — | — | US | claimed |
| US-20200231601-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2020-07-23 | — | — | US | claimed |
| EP-3555086-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | Amgen Inc. (US) | 2019-10-23 | — | — | EP | claimed |
| WO-2018112094-A1 | 1,4-THIAZINE DIOXIDE AND 1,2,4-THIADIAZINE DIOXIDE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND METHODS OF USE | AMGEN INC. (US) | 2018-06-21 | — | — | WO | claimed |
| EP-3911698-A1 | STABILIZER COMPOSITION FOR SEALANTS AND ADHESIVES | BASF SE (DE) | 2021-11-24 | — | — | EP | disclosed |
| CN-110062790-B | Stabilizer composition | 巴斯夫欧洲公司 | 2021-09-24 | — | — | CN | disclosed |
| CN-110062796-B | Hardenable polymer composition | 巴斯夫欧洲公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-113302234-A | Stabilizer composition for sealants and adhesives | 巴斯夫欧洲公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-3526288-B1 | STABILIZER COMPOSITION | BASF SE (DE) | 2021-08-04 | — | — | EP | disclosed |
| EP-3526301-B1 | HARDENABLE POLYMER COMPOSITION | BASF SE (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-11021493-B2 | 1,4-thiazine dioxide and 1,2,4-thiadiazine dioxide derivatives as beta-secretase inhibitors and methods of use | AMGEN INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-11001698-B2 | Stabilizer composition | BASF SE | 2021-05-11 | — | — | US | disclosed |
| US-5330995-A | Fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-19 | — | — | US | disclosed |
| US-5250505-A | Particularly effective against grasses; low application rate; high selectivity; nonphytotoxic when used for broad-leaf crops and rice | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| US-5228896-A | Pre- and postemergence herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1993-07-20 | — | — | US | disclosed |
| US-5190573-A | CYCLOHEXENONE OXIME ETHERS, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-02 | — | — | US | disclosed |
| US-5158598-A | Insecticides, miticides, and nematocides; nonphytotoxic | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-27 | — | — | US | disclosed |
| US-5106408-A | Pre- and postemergence | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| US-5085685-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| US-5022914-A | Pre- and post-emergence; broad leaf plants; rice | BASF AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |