Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.54 |
| ▸ | PPARA | Q07869 | 18/20 | 0.54 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602219 | 0.94 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5657691 | 0.94 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL14602220 | 0.94 | PPARG (0.60) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7009193 | 0.94 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7009669 | 0.94 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7010493 | 0.94 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7004233 | 0.94 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7004348 | 0.94 | PPARG (0.59) | PPARGPPARAPPARDPGRADORA3 | |
| Tert-Butylamine SCHEMBL7001544 | 0.90 | PPARG (0.56) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL7004351 | 0.89 | PPARG (0.53) | PPARGPPARAPPARDPGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363913-A2 | SALTS OF PYRIMIDINE DERIVATIVES FOR USE AGAINST CORONARY HEART DISEASE AND ATHEROSCLEROSE | Dr. Reddy's Laboratories Ltd. (IN) | 2003-11-26 | — | — | EP | claimed |
| WO-2002062798-A2 | SALTS OF PYRIMIDINE DERIVATIVES FOR USE AGAINST CORONARY HEART DISEASE AND ATHEROSCLEROSE | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-08-15 | — | — | WO | claimed |
| EP-1363913-A2 | SALTS OF PYRIMIDINE DERIVATIVES FOR USE AGAINST CORONARY HEART DISEASE AND ATHEROSCLEROSE | Dr. Reddy's Laboratories Ltd. (IN) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062798-A2 | SALTS OF PYRIMIDINE DERIVATIVES FOR USE AGAINST CORONARY HEART DISEASE AND ATHEROSCLEROSE | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-08-15 | — | — | WO | disclosed |