SCHEMBL709746

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6128533	0.98	PARP1 (0.51)	PARP1TNK1TNK2ACKR3MEN1
	SCHEMBL708984	0.98	PARP1 (0.51)	PARP1TNK1TNK2ACKR3MEN1
	SCHEMBL709447	0.92	PARP1 (0.49)	PARP1TNK1TNK2NTRK1ACKR3
	SCHEMBL13285127	0.92	PARP1 (0.48)	PARP1TNK1TNK2ACKR3KDM4E
	SCHEMBL708669	0.91	PARP1 (0.44)	PARP1TNK1TNK2NTRK1ACKR3
	SCHEMBL710877	0.91	PARP1 (0.59)	PARP1NTRK1MEN1KMT2AKDM4E
	SCHEMBL708039	0.91	PARP1 (0.59)	PARP1NTRK1MEN1KMT2AKDM4E
	SCHEMBL708792	0.90	PARP1 (0.52)	PARP1TNK1TNK2ACKR3MEN1
	SCHEMBL710443	0.90	PARP1 (0.50)	PARP1TNK1TNK2ACKR3MEN1
	SCHEMBL709173	0.89	PARP1 (0.48)	PARP1TNK1TNK2NTRK1ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.