Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 3/20 | 1.00 |
| ▸ | CPT1A | P50416 | 3/20 | 1.00 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.61 |
| ▸ | CRAT | P43155 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691261 | 1.00 | CPT2 (1.00) | CPT2CPT1ASLC22A16CRATMEN1 | |
| SCHEMBL3691259 | 1.00 | CPT2 (1.00) | CPT2CPT1ASLC22A16CRATMEN1 | |
| SCHEMBL13409915 | 0.79 | CPT2 (0.65) | CPT2CPT1ASLC22A16MEN1KMT2A | |
| SCHEMBL10415626 | 0.79 | CPT2 (0.65) | CPT2CPT1ASLC22A16CRATMEN1 | |
| SCHEMBL10415627 | 0.79 | CPT2 (0.65) | CPT2CPT1ASLC22A16CRATMEN1 | |
| SCHEMBL10079589 | 0.79 | CPT2 (0.65) | CPT2CPT1ASLC22A16MEN1KMT2A | |
| SCHEMBL10415628 | 0.79 | CPT2 (0.65) | CPT2CPT1ASLC22A16CRATMEN1 | |
| Hydrochloric Acid SCHEMBL3195175 | 0.77 | CPT2 (0.63) | CPT2CPT1ASLC22A16MEN1KMT2A | |
| D-Carnitine SCHEMBL94286 | 0.76 | SLC22A16 (1.00) | CPT2CPT1ASLC22A16CRATMEN1 | |
| Carnitine SCHEMBL3902633 | 0.76 | SLC22A16 (1.00) | CPT2CPT1ASLC22A16CRATMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402322-B1 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | SIGMA TAU IND FARMACEUTI (IT) | 1994-07-06 | — | — | EP | claimed |
| US-5041643-A | Esterifying crotonobetaine chloride with benzyl alcohol, reacting with alpha-methylbenzylamine, resolving, removing benzyl group, forming salt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-08-20 | — | — | US | claimed |
| EP-0402322-A2 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1990-12-12 | — | — | EP | claimed |
| EP-1194398-B1 | SYNTHESIS OF (R) AND (S)-AMINOCARNITINE AND THEIR DERIVATIVES STARTING FROM D- AND L-ASPARTIC ACID | SIGMA TAU IND FARMACEUTI (IT) | 2003-08-27 | — | — | EP | disclosed |
| US-6528684-B1 | Blocking amino group, cyclizing to anhydride, decarbonylation lactonation, hydrolysis, dehydroxylation quaternation using trimethyl ammonium halide, converting to internal carboxylic amine salt and deblocking | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-03-04 | — | — | US | disclosed |
| EP-1194398-A1 | SYNTHESIS OF (R) AND (S)-AMINOCARNITINE AND THEIR DERIVATIVES STARTING FROM D- AND L-ASPARTIC ACID | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002341-A1 | SYNTHESIS OF (R) AND (S)-AMINOCARNITINE AND THEIR DERIVATIVES STARTING FROM D- AND L-ASPARTIC ACID | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2001-01-11 | — | — | WO | disclosed |
| EP-0402322-B1 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | SIGMA TAU IND FARMACEUTI (IT) | 1994-07-06 | — | — | EP | disclosed |
| EP-0402322-B1 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | SIGMA TAU IND FARMACEUTI (IT) | 1994-07-06 | — | — | EP | disclosed |
| US-5041643-A | Esterifying crotonobetaine chloride with benzyl alcohol, reacting with alpha-methylbenzylamine, resolving, removing benzyl group, forming salt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| US-5041643-A | Esterifying crotonobetaine chloride with benzyl alcohol, reacting with alpha-methylbenzylamine, resolving, removing benzyl group, forming salt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| US-5041643-A | Esterifying crotonobetaine chloride with benzyl alcohol, reacting with alpha-methylbenzylamine, resolving, removing benzyl group, forming salt | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 1991-08-20 | — | — | US | disclosed |
| EP-0402322-A3 | PROCESS FOR THE PRODUCTION OF R(+)-AMINOCARNITINE AND S(-)-AMINO-CARNITINE | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-01-02 | — | — | EP | disclosed |
| EP-0402322-A3 | PROCESS FOR THE PRODUCTION OF R(+)-AMINOCARNITINE AND S(-)-AMINO-CARNITINE | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1991-01-02 | — | — | EP | disclosed |
| EP-0402322-A2 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402322-A2 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402322-A2 | Process for the production of R(+)-aminocarnitine and S(-)-amino-carnitine | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1990-12-12 | — | — | EP | disclosed |