Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | NOS3 | P29474 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115158 | 0.85 | MIF (0.61) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL2404477 | 0.83 | MIF (0.59) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL919175 | 0.83 | MIF (0.59) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL13594117 | 0.81 | MIF (0.57) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL9921621 | 0.81 | MIF (0.57) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL28118844 | 0.78 | MIF (0.53) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL2766612 | 0.76 | MIF (0.67) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL727626 | 0.76 | MIF (0.67) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL3915370 | 0.76 | MIF (1.00) | MIFNOS3NOS2LMNAHKDC1 | |
| SCHEMBL6970517 | 0.76 | MIF (0.67) | MIFNOS3NOS2LMNAHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885237-B1 | OLIGONUCLEOTIDE ANALOGUES | ISIS PHARMACEUTICALS INC (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6562960-B1 | Oligonucleotide analogues | ISIS PHARMACEUTICALS, INC. | 2003-05-13 | — | — | US | disclosed |
| EP-0885237-A1 | OLIGONUCLEOTIDE ANALOGUES | Novartis AG (CH) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032887-A1 | OLIGONUCLEOTIDE ANALOGUES | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |