Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 9/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097692 | 1.00 | BCL2 (0.48) | BCL2BAK1HTR7HRH3BCL2L1 | |
| SCHEMBL7097630 | 0.91 | BCL2 (0.49) | BCL2BAK1HTR7HRH3BCL2L1 | |
| SCHEMBL7098309 | 0.91 | BCL2 (0.49) | BCL2BAK1HTR7HRH3BCL2L1 | |
| SCHEMBL7097626 | 0.81 | BCL2 (0.48) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7097662 | 0.81 | BCL2 (0.48) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7103677 | 0.81 | BCL2 (0.48) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7099289 | 0.81 | BCL2 (0.48) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7097646 | 0.81 | BCL2 (0.50) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7100750 | 0.81 | BCL2 (0.50) | BCL2BAK1HTR7BCL2L1 | |
| SCHEMBL7098167 | 0.81 | BCL2 (0.50) | BCL2BAK1HTR7BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |