Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 11/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097801 | 1.00 | TOP2A (0.43) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL7009308 | 0.91 | CYP3A4 (0.47) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL8325067 | 0.91 | CYP3A4 (0.47) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL7013089 | 0.90 | TOP2A (0.54) | TOP2ATOP2BKDM4EGSK3BALDH1A1 | |
| SCHEMBL7095437 | 0.89 | TOP2A (0.43) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL8321408 | 0.89 | TOP2A (0.43) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL7012871 | 0.88 | TOP2A (0.43) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL8317967 | 0.88 | TOP2A (0.43) | TOP2ATOP2BCYP3A4KDM4EGSK3B | |
| SCHEMBL8319164 | 0.87 | TOP2A (0.56) | TOP2ATOP2BCYP3A4KDM4EALDH1A1 | |
| SCHEMBL7009753 | 0.87 | TOP2A (0.56) | TOP2ATOP2BCYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |