Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102061 | 0.96 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4MCHR1HTR1A | |
| SCHEMBL14857951 | 0.95 | MCHR1 (0.44) | SLC6A2SLC6A3SLC6A4MCHR1HTR1A | |
| SCHEMBL25385511 | 0.93 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4MCHR1HTR1A | |
| SCHEMBL12489166 | 0.85 | KAT2B (0.44) | SLC6A2SLC6A3SLC6A4HTR1AAR | |
| SCHEMBL24682361 | 0.84 | POLB (0.39) | SLC6A2SLC6A3SLC6A4HTR1APOLB | |
| SCHEMBL4504051 | 0.82 | KDM4E (0.44) | SLC6A2SLC6A3SLC6A4HTR2CHTR2B | |
| SCHEMBL16333708 | 0.81 | HRH1 (0.41) | SLC6A2SLC6A3MCHR1HTR1APOLB | |
| SCHEMBL29150466 | 0.80 | POLB (0.39) | SLC6A2SLC6A3SLC6A4MCHR1POLB | |
| SCHEMBL19510885 | 0.79 | MCHR1 (0.39) | MCHR1POLBHTR2CHTR2BHRH1 | |
| SCHEMBL13537681 | 0.79 | MCHR1 (0.45) | SLC6A2SLC6A3SLC6A4MCHR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095441-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2003-11-20 | — | — | WO | disclosed |