SCHEMBL7098374

SCHEMBL7098374

CCCc1nn(C)c2c(=O)n(CCOc3ccc(CC(Oc4ccccc4)C(=O)OCC)cc3)c(CC)nc12

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.44
PPARG P37231 10/20 0.41
PPARD Q03181 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096427 0.96 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL7006668 0.94 PPARA (0.43) PPARAPPARGPPARD
SCHEMBL7092433 0.93 PPARG (0.47) PPARAPPARGPPARD
SCHEMBL7096057 0.92 PPARA (0.42) PPARAPPARGPPARD
SCHEMBL7092810 0.91 PPARA (0.44) PPARAPPARGPPARD
SCHEMBL7092279 0.89 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL7096182 0.87 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL7095559 0.87 PPARG (0.46) PPARAPPARGPPARD
SCHEMBL7093366 0.87 PPARA (0.45) PPARAPPARGPPARD
SCHEMBL7091645 0.87 PPARG (0.51) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1363914-A1 ARYL SUBSTITUTED ALKYLCARBOXYLIC ACIDS AS HYPOCHOLESTEROLEMIC AGENTS Dr. Reddy's Laboratories Ltd. (IN) 2003-11-26 EP claimed
US-6444816-B1 DIETETICS, ANTICHOLESTEROL AGENTS, ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2002-09-03 US claimed
WO-2002062799-A1 ARYL SUBSTITUTED ALKYLCARBOXYLIC ACIDS AS HYPOCHOLESTEROLEMIC AGENTS DR. REDDY'S LABORATORIES LTD. (IN) 2002-08-15 WO claimed
US-6444816-B1 DIETETICS, ANTICHOLESTEROL AGENTS, ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2002-09-03 US disclosed