Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.77 |
| ▸ | HTR2B | P41595 | 7/20 | 0.77 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5964636 | 0.99 | HTR2C (0.76) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL7655785 | 0.86 | HTR2C (0.98) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL7660393 | 0.84 | HTR2C (0.76) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL7146484 | 0.83 | HTR2C (0.56) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| SCHEMBL29424927 | 0.80 | MAPT (1.00) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| SCHEMBL496853 | 0.80 | MAPT (1.00) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| SCHEMBL29424773 | 0.80 | MAPT (1.00) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL226068 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL29440043 | 0.79 | HTR2C (1.00) | HTR2CHTR2BHCRTR1MEN1MAPT | |
| SCHEMBL2246120 | 0.75 | POLB (0.75) | HTR2CHTR2BHCRTR1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075478-B1 | PHENYLUREA AND PHENYLTHIO UREA DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |