Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810586 | 1.00 | TP53 (0.36) | TP53TSHRSLC7A5 | |
| SCHEMBL18033707 | 0.81 | — | — | |
| SCHEMBL8583868 | 0.76 | TP53 (0.47) | TP53TSHRSLC7A5 | |
| SCHEMBL8583856 | 0.76 | TP53 (0.47) | TP53TSHRSLC7A5 | |
| SCHEMBL5675218 | 0.76 | TP53 (0.47) | TP53TSHRSLC7A5 | |
| SCHEMBL12951567 | 0.75 | TP53 (0.60) | TP53TSHRSLC7A5 | |
| SCHEMBL14905652 | 0.74 | TP53 (0.31) | TP53 | |
| SCHEMBL1261744 | 0.69 | TP53 (0.50) | TP53TSHRSLC7A5 | |
| SCHEMBL18211012 | 0.69 | TP53 (0.50) | TP53TSHRSLC7A5 | |
| SCHEMBL18033706 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307579-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | Kosan Biosciences, Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012534-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2002-02-14 | — | — | WO | disclosed |