Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.52 |
| ▸ | MAOA | P21397 | 8/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052055 | 0.84 | MAOB (0.54) | MAOBMAOAABCB1 | |
| SCHEMBL6741234 | 0.82 | MAOB (0.52) | MAOBMAOAABCB1 | |
| SCHEMBL6739287 | 0.82 | MAOB (0.55) | MAOBMAOAABCB1 | |
| SCHEMBL6742472 | 0.81 | ABCB1 (0.58) | MAOBMAOAABCB1 | |
| SCHEMBL6737479 | 0.80 | ABCB1 (0.60) | MAOBMAOAABCB1 | |
| SCHEMBL6741749 | 0.79 | ABCB1 (0.54) | MAOBMAOAABCB1CES2 | |
| SCHEMBL6737859 | 0.79 | ABCB1 (0.56) | MAOBMAOAABCB1 | |
| SCHEMBL6739520 | 0.79 | ABCB1 (0.56) | MAOBMAOAABCB1 | |
| SCHEMBL6737485 | 0.79 | MAOB (0.52) | MAOBMAOAABCB1 | |
| SCHEMBL6742959 | 0.79 | ABCB1 (0.61) | MAOBMAOAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320528-A2 | SUBSTITUTED PHTHALIDES AS ANTI-CONVULSIVE DRUGS | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002000638-A2 | SUBSTITUTED PHTHALIDES AS ANTI-CONVULSIVE DRUGS | INSTITUTE OF MATERIA MEDICA (CN) | 2002-01-03 | — | — | WO | disclosed |