Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.59 |
| ▸ | HTR2A | P28223 | 18/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6715326 | 0.84 | HTR2C (0.64) | HTR2CHTR2AHTR2B | |
| SCHEMBL6712325 | 0.81 | HTR2C (0.64) | HTR2CHTR2AHTR2B | |
| SCHEMBL6711548 | 0.81 | HTR2C (0.72) | HTR2CHTR2AHTR2B | |
| SCHEMBL6715429 | 0.80 | HTR2C (0.61) | HTR2CHTR2AHTR2B | |
| SCHEMBL6711560 | 0.80 | HTR2C (0.71) | HTR2CHTR2AHTR2B | |
| SCHEMBL6713042 | 0.79 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL6713915 | 0.79 | HTR2C (0.78) | HTR2CHTR2AHTR2B | |
| SCHEMBL6715619 | 0.79 | HTR2C (0.65) | HTR2CHTR2AHTR2B | |
| SCHEMBL6713637 | 0.78 | HTR2C (0.61) | HTR2CHTR2AHTR2B | |
| SCHEMBL6712388 | 0.78 | HTR2C (0.58) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328525-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-A]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2001072752-A2 | 2,3,4,5-TETRAHYDRO-1H-[1,4]DIAZEPINO[1,7-a]INDOLE COMPOUNDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |