Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.60 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28767042 | 0.89 | CYP1A2 (0.68) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Acetic Acid SCHEMBL7099991 | 0.87 | CYP1A2 (0.76) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Acetic Acid SCHEMBL25361488 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Acetic Acid SCHEMBL10948260 | 0.85 | CYP1A2 (0.73) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Alcohol SCHEMBL27490822 | 0.85 | CYP1A2 (0.79) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| SCHEMBL28270204 | 0.83 | CYP1A2 (0.63) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Propionic Acid SCHEMBL28901988 | 0.83 | AKR1C3 (0.57) | CYP1A2CYP2A6AKR1C3AKR1C2PTGS1 | |
| Methyl Alcohol SCHEMBL5664821 | 0.82 | CYP1A2 (0.91) | CYP1A2CYP2A6KDM4EALDH1A1CYP2C19 | |
| SCHEMBL29353188 | 0.82 | CYP1A2 (1.00) | CYP1A2CYP2A6KDM4EALDH1A1CYP2C19 | |
| SCHEMBL5311432 | 0.82 | CYP1A2 (1.00) | CYP1A2CYP2A6KDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242243-B1 | PURE CULTURE; FOR PRODUCTION OF HYDROLASE ENZYME USEFUL IN EFFICIENT RESOLUTION OF (+)-6-METHOXY-ALPHA-METHYL NAPHTHALENE ACETIC ACID ALKYL ESTERS; PRODUCTION OF NAPROXEN | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-06-05 | — | — | US | claimed |
| EP-0952227-A1 | A bio-resolution process | Council of Scientific and Industrial Research (IN) | 1999-10-27 | — | — | EP | claimed |
| EP-0952227-B1 | A bio-resolution process | COUNCIL SCIENT IND RES (IN) | 2003-09-03 | — | — | EP | disclosed |
| US-6242243-B1 | PURE CULTURE; FOR PRODUCTION OF HYDROLASE ENZYME USEFUL IN EFFICIENT RESOLUTION OF (+)-6-METHOXY-ALPHA-METHYL NAPHTHALENE ACETIC ACID ALKYL ESTERS; PRODUCTION OF NAPROXEN | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2001-06-05 | — | — | US | disclosed |
| EP-0952227-A1 | A bio-resolution process | Council of Scientific and Industrial Research (IN) | 1999-10-27 | — | — | EP | disclosed |