Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999876 | 1.00 | TTR (0.65) | TTRCA1CA2CA12CA9 | |
| SCHEMBL25136853 | 0.83 | TTR (0.67) | TTRCA1CA2CA12CA9 | |
| SCHEMBL13114100 | 0.83 | TTR (0.67) | TTRCA1CA2CA12CA9 | |
| SCHEMBL13994611 | 0.81 | TTR (0.65) | TTRCA1CA2CA12CA9 | |
| SCHEMBL5194875 | 0.81 | TTR (0.65) | TTRCA1CA2CA12CA9 | |
| SCHEMBL5194860 | 0.81 | TTR (0.65) | TTRCA1CA2CA12CA9 | |
| SCHEMBL13083503 | 0.79 | CES1 (0.41) | TTRCA1CA2CA12CA9 | |
| SCHEMBL29072976 | 0.79 | TTR (1.00) | TTRCA1CA2CA12CA9 | |
| SCHEMBL25137097 | 0.79 | TTR (1.00) | TTRCA1CA2CA12CA9 | |
| SCHEMBL12235577 | 0.79 | TTR (1.00) | TTRCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158237-A1 | Combination of antioxidant substances for the treatment of alzheimer's disease | COLBA R & D INC. (CA) | 2003-08-21 | — | — | US | disclosed |