Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459129 | 0.76 | PARP1 (0.54) | PARP1CSNK2A1CSNK2A2CSNK2BKDM4E | |
| SCHEMBL29399562 | 0.74 | TSHR (0.58) | PARP1KDM4EALDH1A1THRBHPGD | |
| SCHEMBL31279968 | 0.74 | TSHR (0.58) | PARP1KDM4EALDH1A1THRBHPGD | |
| SCHEMBL17254441 | 0.74 | TSHR (0.58) | PARP1KDM4EALDH1A1THRBHPGD | |
| SCHEMBL17327572 | 0.73 | TTR (0.50) | PARP1KDM4EALDH1A1THRBHPGD | |
| SCHEMBL29153700 | 0.72 | KDM4E (0.49) | PARP1CSNK2A1CSNK2A2CSNK2BKDM4E | |
| SCHEMBL23830045 | 0.71 | PARP1 (0.68) | PARP1CSNK2A1CSNK2A2CSNK2BKDM4E | |
| SCHEMBL29620678 | 0.71 | PARP1 (0.68) | PARP1CSNK2A1CSNK2A2CSNK2BKDM4E | |
| SCHEMBL69604 | 0.71 | KDM4E (0.67) | PARP1KDM4EALDH1A1THRBHPGD | |
| SCHEMBL30844878 | 0.71 | KDM4E (0.67) | PARP1KDM4EALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893456-B1 | Process for producing modified acrylic rubber | NIPPON MEKTRON KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6380318-B1 | PEROXIDE CURABLE; SOLVENT-FREE | NIPPON MEKTRON, LIMITED (JP) | 2002-04-30 | — | — | US | disclosed |
| EP-0893456-A1 | Process for producing modified acrylic rubber | Nippon Mektron, Limited (JP) | 1999-01-27 | — | — | EP | disclosed |