Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6164335 | 0.84 | F10 (0.56) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6165556 | 0.83 | F10 (0.43) | F10PRSS1SCN9A | |
| SCHEMBL6164340 | 0.83 | F10 (0.39) | F10PRSS1SCN9A | |
| SCHEMBL6163520 | 0.76 | F10 (0.48) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6166094 | 0.75 | F10 (0.37) | F10PRSS1SCN9AF2PRSS2 | |
| SCHEMBL6165684 | 0.74 | F10 (0.43) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6162862 | 0.74 | F10 (0.48) | F10PRSS1 | |
| SCHEMBL6162868 | 0.72 | F10 (0.34) | F10PRSS1SCN9A | |
| SCHEMBL7101291 | 0.72 | F10 (0.55) | F10PRSS1SCN9AF2PRSS2 | |
| SCHEMBL6166521 | 0.72 | F10 (0.50) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | F10 11/4885PRSS1 43/4885SCN9A 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.