SCHEMBL7101658

SCHEMBL7101658

C=C(C)O[Si](OCCCOC(=O)C(=C)C)(OC(=C)C)OC(=C)C

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597402 0.90 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2228744 0.84 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11745747 0.83 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27753211 0.83 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27406725 0.81 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL30708243 0.81 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL182045 0.81 TSHR (0.72) TSHRTHRBPOLBAPEX1HTT
SCHEMBL3366378 0.81 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1046104 0.80 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28743069 0.80 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038934-B1 Base coat composition KANSAI PAINT CO LTD (JP) 2003-09-03 EP disclosed
EP-0768350-B1 Base coat composition for forming topcoat and coating method using same KANSAI PAINT CO LTD (JP) 2002-03-13 EP disclosed
EP-1038934-A2 Base coat composition KANSAI PAINT CO., LTD. (JP) 2000-09-27 EP disclosed
US-5902644-A LAMINATING THE UNDERCOATINGS COMPRISING AT LEAST ONE OF EPOXY-CONTAINING COMPOUND AND CARBOXY-CONTAINING COMPOUND HAVING A HYDROXY GROUP, FORMING A PROTECTIVE COATINGS HAVING ACID RESISTANCE, CHIPPING RESISTANCE, RECOAT ADHESION KANSAI PAINT COMPANY, LIMITED (JP) 1999-05-11 US disclosed
US-5898052-A BASE COAT COMPRISING COMPOUND HAVING TWO EPOXY GROUPS IN ONE MOLECULE, COMPOUND HAVING TWO CARBOXYL GROUPS IN ONE MOLECULE, AT LEAST ONE COMPONENT ALSO HAVING HYDROXYL GROUP, MELAMINE RESIN, PIGMENT KANSAI PAINT COMPANY, LTD. (JP) 1999-04-27 US disclosed
EP-0768350-A2 Base coat composition for forming topcoat and coating method using same KANSAI PAINT CO., LTD. (JP) 1997-04-16 EP disclosed
EP-0173278-B1 ROOM TEMPERATURE-CURABLE RESIN COMPOSITION DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-11-07 EP disclosed
US-4818790-A Room-temperature-curable resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0173278-A2 Room temperature-curable resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-03-05 EP disclosed