SCHEMBL7101676

SCHEMBL7101676

CCCCCC1=CCC[C@@H]1CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 2/20 0.46
TBXA2R P21731 5/20 0.39
ALDH1A1 P00352 2/20 0.39
SCD O00767 1/20 0.39
S1PR1 P21453 6/20 0.35
S1PR3 Q99500 6/20 0.35
S1PR4 O95977 3/20 0.35
S1PR2 O95136 2/20 0.35
S1PR5 Q9H228 2/20 0.34
PPARA Q07869 1/20 0.34
AKR1B1 P15121 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7100309 1.00 PTGER2 (0.46) PTGER2TBXA2RALDH1A1SCDS1PR1
SCHEMBL7054405 0.86 PTGER2 (0.43) PTGER2TBXA2RSCDS1PR1S1PR3
SCHEMBL7943227 0.84 PTGER2 (0.49) PTGER2TBXA2RALDH1A1PPARA
SCHEMBL7987075 0.82 PTGER2 (0.51) PTGER2TBXA2RALDH1A1PPARA
SCHEMBL7156105 0.80 PTGER2 (0.38) PTGER2TBXA2R
SCHEMBL7051766 0.78 PTGER2 (0.39) PTGER2TBXA2RALDH1A1
SCHEMBL5964829 0.78 PTGER2 (0.45) PTGER2TBXA2RALDH1A1SCDS1PR1
SCHEMBL7113174 0.75 TBXA2R (0.42) TBXA2RALDH1A1PPARAHPGDHSD17B10
SCHEMBL6538704 0.75 PTGER2 (0.34) PTGER2TBXA2R
SCHEMBL7110403 0.74 PTGER2 (0.46) PTGER2ALDH1A1SCDS1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841331-B1 New epoxides, process for their preparation and their use for the preparation of perfume ingredients FIRMENICH & CIE (CH) 2003-01-08 EP claimed
US-5962706-A ORGANOLEPTICS FIRMENICH SA (CH) 1999-10-05 US claimed
EP-0841331-A2 New epoxides, process for their preparation and their use for the preparation of perfume ingredients FIRMENICH SA (CH) 1998-05-13 EP claimed
EP-1048643-B1 Process for the preparation of chiral epoxides FIRMENICH & CIE (CH) 2003-10-22 EP disclosed
EP-0841331-B1 New epoxides, process for their preparation and their use for the preparation of perfume ingredients FIRMENICH & CIE (CH) 2003-01-08 EP disclosed
US-6262288-B1 Process for the preparation of chiral epoxides FIRMENICH SA (CH) 2001-07-17 US disclosed
US-6177589-B1 PREPARING A CYCLANIC 1R ALKYL 2-(HYDROCARBYL-3-KETOCYCLO-PENTYLACETATE, E.G. CIS-HEDIONE.RTM, BY TREATING A CYCLANIC 1R ALKYL ESTER OF A 2-(2-HYDROCARBYL-2,3-EPOXYCYCLOPENTYL IN A SOLVENT WITH A LEWIS ACID OR ACIDIC CLAY FIRMENICH SA (CH) 2001-01-23 US disclosed
EP-1048643-A1 Process for the preparation of chiral epoxides FIRMENICH SA (CH) 2000-11-02 EP disclosed
US-5962706-A ORGANOLEPTICS FIRMENICH SA (CH) 1999-10-05 US disclosed
EP-0841331-A2 New epoxides, process for their preparation and their use for the preparation of perfume ingredients FIRMENICH SA (CH) 1998-05-13 EP disclosed