Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 19/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823301 | 1.00 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1821147 | 0.99 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1821359 | 0.95 | HIF1A (0.36) | — | |
| SCHEMBL1820629 | 0.95 | HIF1A (0.36) | — | |
| SCHEMBL1821149 | 0.94 | ITGB1 (0.38) | ITGB1ITGA4 | |
| SCHEMBL1821054 | 0.92 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7106236 | 0.92 | ITGB1 (0.39) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1818339 | 0.91 | ITGB1 (0.38) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7106468 | 0.91 | ITGB1 (0.41) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7416547 | 0.91 | ITGB1 (0.48) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183241-B1 | SPIROIMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM | AVENTIS PHARMA GMBH (DE) | 2003-09-17 | — | — | EP | claimed |