Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PPARA | Q07869 | 7/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101627 | 0.94 | PPARG (0.51) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL376998 | 0.86 | PPARG (0.65) | PPARDPPARGPPARANR1H4 | |
| SCHEMBL5846365 | 0.86 | PPARD (0.46) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL5845148 | 0.85 | PPARD (0.45) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL30003783 | 0.85 | PPARD (0.45) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL24658486 | 0.85 | PPARD (0.45) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL30003787 | 0.85 | PPARD (0.45) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL1765909 | 0.84 | PPARD (0.46) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL5845397 | 0.83 | PPARD (0.44) | PPARDPPARGPPARATP53NR1H4 | |
| SCHEMBL376890 | 0.82 | PPARG (0.49) | PPARDPPARGPPARATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1371650-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2003-12-17 | — | — | EP | disclosed |