Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339530 | 0.91 | GSK3B (0.46) | GSK3BHTR1AHRH3 | |
| SCHEMBL5344105 | 0.90 | HRH3 (0.47) | HTR1AHRH3 | |
| SCHEMBL5331604 | 0.84 | GSK3B (0.52) | GSK3BHTR1A | |
| SCHEMBL5331696 | 0.80 | HRH3 (0.51) | HTR1ASLC6A4HRH3 | |
| Hydrochloric Acid SCHEMBL6222193 | 0.79 | HRH3 (0.50) | HTR1ASLC6A4HRH3 | |
| SCHEMBL5335316 | 0.78 | HRH3 (0.43) | GSK3BHTR1AHRH3 | |
| SCHEMBL5335731 | 0.77 | HRH3 (0.46) | HTR1AHRH3 | |
| SCHEMBL5332684 | 0.75 | HRH3 (0.50) | HTR1ASLC6A4HRH3 | |
| SCHEMBL5332653 | 0.73 | HRH3 (0.43) | GSK3BHTR1AHRH3 | |
| SCHEMBL5332597 | 0.71 | PARP1 (0.47) | HTR1ASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278741-A1 | MUSCARINIC AGONISTS | Acadia Pharmaceuticals Inc. (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001083472-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2001-11-08 | — | — | WO | claimed |