Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7103623 | 0.97 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL7103630 | 0.92 | ADORA2A (0.46) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7105567 | 0.88 | ADORA2A (0.50) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL7103945 | 0.86 | ADORA2A (0.50) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL6839241 | 0.86 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| Formic Acid SCHEMBL7104995 | 0.85 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7098449 | 0.84 | ADORA2A (0.52) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL7100461 | 0.84 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| SCHEMBL5086039 | 0.84 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2BPGK1 | |
| Formic Acid SCHEMBL7104785 | 0.84 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2BPGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | claimed |