⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514969 | 0.96 | — | — | |
| SCHEMBL29136206 | 0.67 | — | — | |
| SCHEMBL2683 | 0.65 | — | — | |
| SCHEMBL171853 | 0.64 | HDAC8 (0.47) | — | |
| SCHEMBL21640917 | 0.63 | — | — | |
| 2-Mercaptopyrimidine SCHEMBL28494292 | 0.62 | — | — | |
| SCHEMBL17144230 | 0.61 | HDAC8 (0.44) | — | |
| Iodide SCHEMBL28731796 | 0.61 | HDAC8 (0.44) | — | |
| SCHEMBL4270187 | 0.61 | HDAC8 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6535289 | 0.61 | HDAC8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5255 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | claimed |
| WO-2024133551-A1 | PESTICIDALLY ACTIVE PYRIDAZINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-06-27 | — | — | WO | claimed |
| CN-115135656-B | Furanoindazole derivatives | 拜耳公司 | 2024-06-14 | — | — | CN | claimed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | claimed |
| WO-2024110554-A1 | N-[(1 -[2-[6-(PYRIDAZIN-3-YL]-1,2,4-TRIAZOL-3-YL]ETHYL]-QUINAZOLIN-4-AMINE AND N-[1-[3-(6-(PYRIDAZIN-3-YL)PYRAZIN-2-YL]ETHYL]-8-QUINAZOLIN-4-AMINE DERIVATIVES AS PESTICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-30 | — | — | WO | claimed |
| EP-4368625-A1 | SHP2 INHIBITOR AND USE THEREOF | Kanaph Therapeutics Inc. (KR) | 2024-05-15 | — | — | EP | claimed |
| WO-2024083705-A1 | FUROINDAZOLE DERIVATIVES FOR THE TREATMENT OF PAIN | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-25 | — | — | WO | claimed |
| CN-117916242-A | SHP2 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2024022481-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF | 苏中药业集团股份有限公司 | 2024-02-01 | — | — | WO | claimed |
| EP-4304713-A1 | HETEROCYCLIC RIP1 KINASE INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2024-01-17 | — | — | EP | claimed |
| EP-0411183-A1 | Ascorbic acid derivative | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1991-02-06 | — | — | EP | claimed |
| EP-0411184-A1 | Ascorbic acid derivative | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1991-02-06 | — | — | EP | claimed |
| EP-0400403-A2 | N-aryl-nitrogen-heterocycles | BAYER AG (DE) | 1990-12-05 | — | — | EP | claimed |
| EP-0247477-B1 | 1,2,3,6-TETRAHYDRO-5-NITRO-PYRIMIDINE DERIVATIVES | BAYER AG (DE) | 1990-06-27 | — | — | EP | claimed |
| US-4831036-A | INSECTICIDES, NEMATICIDES, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-16 | — | — | US | claimed |
| CN-87103967-A | 1,2,3,6-tetrahydrochysene-5-nitro-pyrimidine derivatives | — | 1987-12-16 | — | — | CN | claimed |
| EP-0247477-A1 | 1,2,3,6-Tetrahydro-5-nitro-pyrimidine derivatives | BAYER AG (DE) | 1987-12-02 | — | — | EP | claimed |
| EP-0237917-A2 | 1,1-Disubstituted cyclopropane derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | claimed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | claimed |
| EP-0014976-B1 | N-SUBSTITUTED 2-CYANAZIRIDINES, METHODS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM, CORRESPONDINGLY SUBSTITUTED AZIRIDINE-2-CARBONAMIDES AND THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1982-04-07 | — | — | EP | claimed |