Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102410 | 1.00 | ADORA2A (0.67) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| Formic Acid SCHEMBL7099699 | 0.97 | ADORA2A (0.65) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| Formic Acid SCHEMBL7099692 | 0.97 | ADORA2A (0.65) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7103703 | 0.92 | ADORA2A (0.68) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7103705 | 0.92 | ADORA2A (0.68) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7099343 | 0.91 | ADORA2A (0.69) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7099345 | 0.91 | ADORA2A (0.69) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7099695 | 0.91 | ADORA2A (0.60) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| SCHEMBL7099694 | 0.91 | ADORA2A (0.59) | ADORA2ACCNB2CCNE2CDK1CDK4 | |
| Formic Acid SCHEMBL7105215 | 0.89 | ADORA2A (0.66) | ADORA2ACCNB2CCNE2CDK1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090023-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-09-10 | — | — | EP | claimed |