Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14652936 | 1.00 | RECQL (0.53) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL7524000 | 1.00 | RECQL (0.53) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL6301674 | 0.81 | RECQL (0.49) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL6301677 | 0.81 | RECQL (0.49) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL5284839 | 0.80 | RECQL (0.54) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL1915837 | 0.80 | RECQL (0.69) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL7524611 | 0.80 | RECQL (0.54) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL16449689 | 0.80 | RECQL (0.54) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL6307440 | 0.80 | RECQL (0.54) | RECQLMEN1KMT2AAKR1C3CYP3A4 | |
| SCHEMBL1915838 | 0.80 | RECQL (0.69) | RECQLMEN1KMT2AAKR1C3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937710-B1 | Method for producing an optically active phenylpropionic acid derivative | AJINOMOTO KK (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-0906901-B1 | Process for producing propionic acid derivatives | AJINOMOTO KK (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6339170-B2 | CONDENSATION OF 2-HYDROXYMETHYL-3-PHENYLPROPIONIC ACID AND GLYCINE BENZYL ESTER, CONVERSION OF HYDROXYL GROUP TO ELIMINATION GROUP, SUBSTITUTION BY ACETYLTHIO GROUP; ENKEPHALIN AND ACETYLCHOLINESTERASE INHIBITORS | AJINOMOTO CO., INC. (JP) | 2002-01-15 | — | — | US | disclosed |
| US-20010014754-A1 | Method for producing optically active phenylpropionic acid derivative | AJINOMOTO CO., INC. (JP) | 2001-08-16 | — | — | US | disclosed |
| US-6242635-B1 | THROUGH SHORT SYNTHESIS ROUTE INDUSTRIALLY SAFE AND EASILY; USED IN PRODUCING OPTICALLY ACTIVE SUBSTANCE CONVERTIBLE INTO A LENIN INHIBITOR INTERMEDIATE, ENKEPHALINASE INHIBITOR, OR PROTEASE INHIBITOR | AJINOMOTO CO., INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6239305-B1 | REACTING A N-ACYLAMINO ACID ESTER WITH A THIOACETIC ACID | AJINOMOTO CO., INC. (JP) | 2001-05-29 | — | — | US | disclosed |
| US-6031121-A | Method for producing optically active phenylpropionic acid derivative | AJINOMOTO CO., INC. (JP) | 2000-02-29 | — | — | US | disclosed |
| EP-0937710-A1 | Method for producing an optically active phenylpropionic acid derivative | Ajinomoto Co., Inc. (JP) | 1999-08-25 | — | — | EP | disclosed |
| EP-0906901-A2 | Process for producing propionic acid derivatives | Ajinomoto Co., Inc. (JP) | 1999-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014754-A1 | Method for producing optically active phenylpropionic acid derivative | ACE, DNPEP, AGT | RECQL 4840/4885MEN1 2252/4885KMT2A 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.