Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103482 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7103586 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7102118 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7098691 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7103072 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL5187382 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL7105359 | 1.00 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11408009 | 0.97 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL11400311 | 0.97 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL15348640 | 0.97 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-1020437-A1 | PROCESS FOR PRODUCING HALOGENOALKYLSULFONAMIDE DERIVATIVES | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |