Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL961 | 0.88 | — | — | |
| Silver SCHEMBL1326350 | 0.88 | MEN1 (0.75) | — | |
| Silver SCHEMBL11662650 | 0.82 | MEN1 (0.67) | — | |
| Ammonia Solution, Strong SCHEMBL159333 | 0.82 | — | — | |
| Silver SCHEMBL6897201 | 0.82 | MEN1 (0.67) | — | |
| Silver SCHEMBL11658534 | 0.82 | MEN1 (0.67) | — | |
| Silver SCHEMBL646022 | 0.82 | — | — | |
| Silver SCHEMBL1045101 | 0.82 | MEN1 (0.67) | — | |
| Silver SCHEMBL2253632 | 0.82 | MEN1 (0.67) | — | |
| Silver SCHEMBL4475369 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107937-B1 | PROCESS FOR THE PRODUCTION OF CYCLOBUTYL HALIDES | EASTMAN CHEM CO (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-1107937-A1 | PROCESS FOR THE PRODUCTION OF CYCLOBUTYL HALIDES | EASTMAN CHEMICAL COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012452-A1 | PROCESS FOR THE PRODUCTION OF CYCLOBUTYL HALIDES | EASTMAN CHEMICAL COMPANY (US) | 2000-03-09 | — | — | WO | disclosed |
| US-5905176-A | Process for the production of cyclobutyl halides | EASTMAN CHEMICAL COMPANY (US) | 1999-05-18 | — | — | US | disclosed |