Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104421 | 1.00 | TAAR1 (0.49) | TAAR1GRIN2BGRIN1HTR3EHTR3B | |
| SCHEMBL7760203 | 1.00 | TAAR1 (0.49) | TAAR1GRIN2BGRIN1HTR3EHTR3B | |
| SCHEMBL9219195 | 0.85 | MIF (0.41) | TAAR1GRIN2BGRIN1SMN1; SMN2IDO1 | |
| SCHEMBL9219198 | 0.85 | MIF (0.41) | TAAR1GRIN2BGRIN1SMN1; SMN2IDO1 | |
| SCHEMBL7763107 | 0.82 | GRIN2B (0.47) | GRIN2BGRIN1IDO1 | |
| SCHEMBL7765314 | 0.80 | TAAR1 (0.53) | TAAR1GRIN2BSMN1; SMN2IDO1HRH3 | |
| SCHEMBL7765310 | 0.80 | TAAR1 (0.53) | TAAR1GRIN2BSMN1; SMN2IDO1HRH3 | |
| SCHEMBL15000001 | 0.79 | GRIN2B (0.54) | GRIN2BSMN1; SMN2IDO1 | |
| SCHEMBL15000004 | 0.79 | GRIN2B (0.54) | GRIN2BSMN1; SMN2IDO1 | |
| SCHEMBL8666179 | 0.77 | TAAR1 (0.45) | TAAR1GRIN2BGRIN1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934929-B1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(arylmethylene)-1-chloro-1-(perfluoroalkyl) methylamine compounds | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6133455-A | INSECTICIDAL AND ACARICIDAL AGENTS; PREPARED FROM N-(ARYLMETHYLENE)-1-CHLORO-1-(PERFLUOROALKYL) METHYLAMINE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6034273-A | INSECTICIDES; MITICIDES | AMERICAN CYANAMID COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0934929-A1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(arylmethylene)-1-chloro-1-(perfluoroalkyl) methylamine compounds | American Cyanamid Company (US) | 1999-08-11 | — | — | EP | disclosed |