Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 16/20 | 0.71 |
| ▸ | PRKCG | P05129 | 4/20 | 0.50 |
| ▸ | CDK1 | P06493 | 4/20 | 0.50 |
| ▸ | PRKACA | P17612 | 4/20 | 0.50 |
| ▸ | AKT2 | P31751 | 4/20 | 0.50 |
| ▸ | AKT3 | Q9Y243 | 4/20 | 0.50 |
| ▸ | PRKACG | P22612 | 3/20 | 0.50 |
| ▸ | PRKACB | P22694 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855665 | 0.83 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL7104447 | 0.81 | AKT1 (0.78) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL4659627 | 0.68 | AKT1 (0.74) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL4824211 | 0.68 | AKT1 (0.74) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL6849854 | 0.67 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL4660652 | 0.66 | AKT1 (0.70) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL6857580 | 0.65 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL6853440 | 0.65 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL6849637 | 0.65 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 | |
| SCHEMBL6853446 | 0.65 | AKT1 (1.00) | AKT1PRKCGCDK1PRKACAAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187026-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187026-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | AKT1 119/4885PRKCG 152/4885CDK1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.