Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 14/20 | 0.41 |
| ▸ | F2 | P00734 | 14/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 13/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 13/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166095 | 0.95 | F10 (0.42) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7101266 | 0.90 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7107547 | 0.87 | F10 (0.37) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6164925 | 0.84 | F10 (0.46) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7108370 | 0.84 | F10 (0.58) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7102295 | 0.83 | F10 (0.49) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7101673 | 0.82 | F10 (0.44) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6163134 | 0.81 | F10 (0.38) | F10ATRKMT2A | |
| SCHEMBL6164425 | 0.78 | F10 (0.54) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7106445 | 0.77 | F10 (0.42) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | F10 11/4885PRSS1 43/4885F2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.