Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900681 | 0.91 | EGLN3 (0.49) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7278106 | 0.88 | EGLN3 (0.46) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10365929 | 0.86 | EGLN3 (0.45) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL4291631 | 0.85 | EGLN3 (0.48) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5899076 | 0.84 | EGLN3 (0.55) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22234971 | 0.77 | EGLN3 (0.48) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6656016 | 0.76 | MEN1 (0.48) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3240872 | 0.76 | EGLN3 (0.44) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5746694 | 0.76 | — | — | |
| SCHEMBL10514858 | 0.74 | EGLN3 (0.65) | EGLN3CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343785-A2 | USE OF SUBSTITUTED IMIDAZOAZINES, NOVEL IMIDAZOAZINES, METHODS FOR THE PRODUCTION THEREOF, AND AGENTS CONTAINING THESE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048146-A2 | USE OF SUBSTITUTED IMIDAZOAZINES, NOVEL IMIDAZOAZINES, METHODS FOR THE PRODUCTION THEREOF, AND AGENTS CONTAINING THESE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | WO | disclosed |
| EP-0144033-A2 | Substituted 5-cycloalkyl-2,2-dimethyl-pentan-3-one | BAYER AG (DE) | 1985-06-12 | — | — | EP | disclosed |