Ornithine

Ornithine

SCHEMBL7105810

NCCCC[C@H](NO)C(=O)O.NCCC[C@H](N)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.69
FOLH1 Q04609 1/20 0.49
NOD1 Q9Y239 5/20 0.44
ARG2 P78540 4/20 0.44
ARG1 P05089 3/20 0.44
RNPEP Q9H4A4 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine Aketoglutarate SCHEMBL7105807 1.00 GSR (0.69) GSRFOLH1NOD1ARG2ARG1
Lysine SCHEMBL1130394 0.98 GSR (0.71) GSRFOLH1NOD1ARG2ARG1
Lysine SCHEMBL9556358 0.98 GSR (0.71) GSRFOLH1NOD1ARG2ARG1
(S)-2-Aminoadipic Acid SCHEMBL15156053 0.91 GSR (0.61) GSRFOLH1NOD1SLC6A5
Norleucine SCHEMBL17423937 0.91 GSR (0.61) GSRFOLH1NOD1SLC6A5
(S)-2-Aminoadipic Acid SCHEMBL15156054 0.91 GSR (0.61) GSRFOLH1NOD1SLC6A5
SCHEMBL48407 0.89 FOLH1 (0.58) GSRFOLH1RNPEPSLC6A5
SCHEMBL1054672 0.89 FOLH1 (0.58) GSRFOLH1RNPEPSLC6A5
SCHEMBL48406 0.89 FOLH1 (0.58) GSRFOLH1RNPEPSLC6A5
Serine SCHEMBL3065485 0.88 GSR (0.56) GSRFOLH1NOD1ARG2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0981318-B1 COMPOSITION FOR TREATING HAIR OREAL (FR) 2003-07-09 EP disclosed
EP-1113778-A2 NON-IRRITATING CLEANSING COMPOSITION Color Access, Inc. (US) 2001-07-11 EP disclosed
US-6239088-B1 CLEANSING COMPOSITION COMPRISING IONIC AQUEOUS BASE CONTAINING AT LEAST ONE ELECTROLYTE, BASIC PROTEIN OR AMINO ACID IN AMOUNT SUFFICIENT TO BUFFER COMPOSITION, PRIMARY SURFACTANT COMPRISING MUCOMIMETIC CONTAINING SIALIC ACID COMPONENT COLOR ACCESS, INC. 2001-05-29 US disclosed
WO-2000056273-A2 NON-IRRITATING CLEANSING COMPOSITION COLOR ACCESS, INC. (US) 2000-09-28 WO disclosed