Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107309 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7110857 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7112210 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7110862 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7106044 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7112142 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7111096 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL7110673 | 1.00 | CA1 (0.36) | CA1CA9SMN1; SMN2FKBP1AFKBP4 | |
| SCHEMBL14410331 | 0.83 | — | — | |
| SCHEMBL5244917 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220850-B1 | 1,4-DIOXACYCLOALKANE-2-ONE AND 1,4-DIOXACYCLOALKENE-2-ONE | SYMRISE GMBH & CO KG (DE) | 2003-10-08 | — | — | EP | claimed |
| US-6573391-B1 | Use in functional perfumery and in fine perfumery; musk scent | HAARMANN & REIMER GMBH (DE) | 2003-06-03 | — | — | US | claimed |
| EP-1220850-B1 | 1,4-DIOXACYCLOALKANE-2-ONE AND 1,4-DIOXACYCLOALKENE-2-ONE | SYMRISE GMBH & CO KG (DE) | 2003-10-08 | — | — | EP | disclosed |
| US-6573391-B1 | Use in functional perfumery and in fine perfumery; musk scent | HAARMANN & REIMER GMBH (DE) | 2003-06-03 | — | — | US | disclosed |
| EP-1220850-A2 | 1,4-DIOXACYCLOALKANE-2-ONE AND 1,4-DIOXACYCLOALKENE-2-ONE | HAARMANN & REIMER GMBH (DE) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001023373-A2 | 1,4-DIOXACYCLOALKANE-2-ONE AND 1,4-DIOXACYCLOALKENE-2-ONE | HAARMANN & REIMER GMBH (DE) | 2001-04-05 | — | — | WO | disclosed |