Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.53 |
| ▸ | TMPRSS11D | O60235 | 8/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7140906 | 0.99 | F2 (0.54) | F2TMPRSS11DF10PLGTMPRSS6 | |
| SCHEMBL7102500 | 0.92 | F2 (0.51) | F2TMPRSS11DF10PLGTMPRSS6 | |
| SCHEMBL7105056 | 0.92 | F2 (0.46) | F2F10PLG | |
| SCHEMBL7102491 | 0.90 | F2 (0.42) | F2TMPRSS11DNPSR1 | |
| SCHEMBL7463647 | 0.88 | F2 (0.42) | F2TMPRSS11DPLGNPSR1 | |
| Hydrochloric Acid SCHEMBL7156977 | 0.87 | F2 (0.43) | F2TMPRSS11DNPSR1 | |
| SCHEMBL7102567 | 0.86 | F2 (0.45) | F2F10PLG | |
| SCHEMBL7107383 | 0.85 | F2 (0.55) | F2TMPRSS11DNPSR1 | |
| Hydrochloric Acid SCHEMBL9228074 | 0.85 | F2 (0.56) | F2TMPRSS11DNPSR1 | |
| SCHEMBL7148741 | 0.84 | F2 (0.61) | F2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361212-A1 | Peptide derivatives as antithrombotic agents | AstraZeneca AB (SE) | 2003-11-12 | — | — | EP | claimed |
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |
| EP-0672658-A1 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1995-09-20 | — | — | EP | claimed |
| WO-1995023609-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1995-09-08 | — | — | WO | claimed |