SCHEMBL710629

SCHEMBL710629

O=C(O)CCCC[C@H]1[C@H]2NC(=O)N[C@H]2CS1(=O)=O

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.56
ABL1 P00519 2/20 0.56
IDE P14735 2/20 0.56
RIN1 Q13671 2/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
PKM P14618 1/20 0.56
MAPK1 P28482 1/20 0.56
KMT2A Q03164 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
PPARG P37231 1/20 0.43
NR2E3 Q9Y5X4 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
HLCS P50747 6/20 0.36
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
CA9 Q16790 3/20 0.32
FOLH1 Q04609 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14563008 1.00 TDP1 (0.56) TDP1ABL1IDERIN1MEN1
SCHEMBL19751695 1.00 TDP1 (0.56) TDP1ABL1IDERIN1MEN1
SCHEMBL13049589 1.00 TDP1 (0.56) TDP1ABL1IDERIN1MEN1
SCHEMBL19751702 0.89 TDP1 (0.48) TDP1ABL1IDERIN1MEN1
SCHEMBL4965653 0.89 TDP1 (0.48) TDP1ABL1IDERIN1MEN1
SCHEMBL3793600 0.86 TDP1 (0.56) TDP1ABL1IDERIN1MEN1
SCHEMBL4970357 0.85 TDP1 (0.39) TDP1ABL1IDERIN1MEN1
SCHEMBL19751691 0.85 TDP1 (0.39) TDP1ABL1IDERIN1MEN1
SCHEMBL18501097 0.85 TDP1 (0.39) TDP1ABL1IDERIN1MEN1
SCHEMBL4965402 0.84 TDP1 (0.59) TDP1ABL1IDERIN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119395003-A Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-02-07 CN claimed
US-20250027947-A1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-01-23 US claimed
CN-112424589-B Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-01-14 CN claimed
EP-3830556-B1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2024-11-13 EP claimed
US-12140596-B2 Kits, microfluidics devices, and methods for performing biotin assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-11-12 US claimed
EP-4416303-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL Blink AG (DE) 2024-08-21 EP claimed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 CN claimed
US-20240084354-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST HONING BIOSCIENCES (FR) 2024-03-14 US claimed
EP-4244240-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST Honing Biosciences (FR) 2023-09-20 EP claimed
WO-2023154852-A1 ANTIBODY BARCODED BEADS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-08-17 WO claimed
WO-2000072802-A2 WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS UNIVERSITY OF WASHINGTON (US) 2000-12-07 WO claimed
US-6075010-A Small molecular weight ligand-hexose containing clearing agents NEORX CORPORATION (US) 2000-06-13 US claimed
EP-0743956-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-03-24 EP claimed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP claimed
EP-0717848-A1 BIOTIN-ANALOG CONJUGATED ANTIBODIES FOR POSITIVE CELL SELECTION AND RELEASE BAXTER INTERNATIONAL INC. (US) 1996-06-26 EP claimed
WO-1995015978-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO claimed
WO-1995007466-A2 BIOTIN-ANALOG CONJUGATED ANTIBODIES FOR POSITIVE CELL SELECTION AND RELEASE BAXTER INTERNATIONAL INC. (US) 1995-03-16 WO claimed
EP-0088542-B1 SKIN TREATMENT COMPOSITION UNILEVER N.V. (NL) 1988-05-11 EP claimed
US-4529587-A Using biotin antagonist LEVER BROTHERS COMPANY (US) 1985-07-16 US claimed
EP-0088542-A2 Skin treatment composition UNILEVER N.V. (NL) 1983-09-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240084354-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST PHAX, SCAMP2, YIPF5 TDP1 2678/4885ABL1 4402/4885IDE 3003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.