Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL3159975 | 1.00 | TSHR (0.46) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL5654265 | 0.95 | TSHR (0.42) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL5437322 | 0.92 | HSD17B10 (0.42) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL10729436 | 0.90 | TSHR (0.59) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL9343615 | 0.89 | TSHR (0.38) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL7521917 | 0.86 | TSHR (0.54) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL9067584 | 0.85 | TSHR (0.47) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Itaconate SCHEMBL6913753 | 0.85 | HSD17B10 (0.60) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| SCHEMBL29015789 | 0.84 | TSHR (0.56) | TSHRHPGDHCAR2ALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL9818307 | 0.84 | TSHR (0.48) | TSHRHPGDHCAR2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1369224-A1 | Light emitting diode signs and translucent plastic sheets used therein | Atofina (FR) | 2003-12-10 | — | — | EP | disclosed |
| EP-1348539-A2 | A mar resistant, non-glare transparent acrylic sheet with consistent optical properties at various sheet thicknesses | Atofina Chemicals, Inc. (US) | 2003-10-01 | — | — | EP | disclosed |