Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.53 |
| ▸ | F9 | P00740 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166700 | 0.94 | F10 (0.51) | F10F9NAMPTALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL6164329 | 0.83 | DEGS1 (0.46) | F10NAMPTALDH1A1LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL6167447 | 0.78 | F10 (0.50) | F10PRSS1F2DEGS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6163953 | 0.78 | F10 (0.51) | F10PRSS1F2DEGS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6163009 | 0.78 | F10 (0.51) | F10PRSS1F2DEGS1PRSS2 | |
| SCHEMBL6166706 | 0.76 | NAMPT (0.45) | NAMPTALDH1A1LMNAGAAHTT | |
| SCHEMBL6163382 | 0.75 | NAMPT (0.45) | F10NAMPTALDH1A1LMNAGAA | |
| Trifluoroacetic Acid SCHEMBL6165358 | 0.74 | F10 (0.50) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL6166608 | 0.74 | F10 (0.43) | F10PRSS1F2DEGS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6165729 | 0.74 | F10 (0.55) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | F10 11/4885F9 23/4885NAMPT 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.