Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7106592 | 1.00 | GRM2 (0.34) | GRM2PDE3BPDE3ASMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL6161844 | 0.94 | PDE3B (0.38) | PDE3BPDE3ASMN1; SMN2KMT2ATSHR | |
| Trifluoroacetic Acid SCHEMBL6161851 | 0.94 | PDE3B (0.38) | PDE3BPDE3ASMN1; SMN2KMT2ATSHR | |
| Trifluoroacetic Acid SCHEMBL6167880 | 0.93 | SMN1; SMN2 (0.34) | PDE3BPDE3ASMN1; SMN2KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL6167885 | 0.93 | SMN1; SMN2 (0.34) | PDE3BPDE3ASMN1; SMN2KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL6165985 | 0.92 | KLKB1 (0.33) | PDE3BPDE3ASMN1; SMN2KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL6165992 | 0.92 | KLKB1 (0.33) | PDE3BPDE3ASMN1; SMN2KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL6164140 | 0.92 | PDE3B (0.32) | GRM2PDE3BPDE3ASMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL6164145 | 0.92 | PDE3B (0.32) | GRM2PDE3BPDE3ASMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL6165679 | 0.90 | EPHX2 (0.40) | MAPTF10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | claimed |
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | GRM2 4707/4885PDE3B 211/4885PDE3A 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.