Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7109068 | 0.95 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Bromide SCHEMBL7109886 | 0.95 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Fluoride Ion SCHEMBL7113552 | 0.78 | KMT2A (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL7113363 | 0.72 | KMT2A (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Bromide SCHEMBL7111100 | 0.72 | KMT2A (0.42) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4819182 | 0.72 | — | — | |
| SCHEMBL6634673 | 0.71 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1643947 | 0.71 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| Water SCHEMBL29155573 | 0.69 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL42695 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0834514-B1 | Process for synthesizing metallocene compounds | KANTO KAGAKU (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-5892075-A | Process for synthesizing metallocene compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0834514-A2 | Process for synthesizing metallocene compounds | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1998-04-08 | — | — | EP | disclosed |