Styrene

Styrene

SCHEMBL7107535

C=Cc1ccccc1.CCCCCCCCCCCCC=C(C)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
AKR1C3 P42330 1/20 0.44
LMNA P02545 1/20 0.42
TBXAS1 P24557 2/20 0.42
EGFR P00533 1/20 0.42
SOAT2 O75908 1/20 0.41
SOAT1 P35610 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
EPHX2 P34913 3/20 0.39
FAAH O00519 2/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
NAAA Q02083 3/20 0.37
ELANE P08246 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8350502 1.00 EP300 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL7780531 1.00 EP300 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL8533290 1.00 EP300 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL6545144 1.00 EP300 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL9354663 1.00 EP300 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL28624612 0.96 EP300 (0.43) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL28173637 0.96 AKR1C3 (0.42) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL3141180 0.94 AKR1C3 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL393960 0.94 AKR1C3 (0.46) EP300TDP1AKR1C3LMNATBXAS1
Styrene SCHEMBL8352287 0.90 AKR1C3 (0.42) EP300TDP1AKR1C3LMNATBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0454980-B1 Encapsulated toners and processes thereof XEROX CORP (US) 1998-08-05 EP claimed
EP-1021472-B1 POLYMER COMPOSITION NAT STARCH CHEM INVEST (US) 2003-10-22 EP disclosed
US-6372846-B1 A POLY(ALKYL(METH)ACRYLATE) BASE POLYMER AND A RUBBER TOUGHENING AGENT PRESENT AS DISCRETE ISLANDS AND SUB-ISLANDS, CONFINED BY THE BASE POLYMER; MOULDINGS; IMPACT STRENGTH; EXTERNAL LIGHT CLUSTERS FOR AUTOMOBILES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2002-04-16 US disclosed
EP-1021472-A1 POLYMER COMPOSITION Ineos Acrylics UK Limited (GB) 2000-07-26 EP disclosed
US-5993909-A COMPRISING EPOXY GROUP CONTAINING MODIFIED POLYESTER AND A COMPOUND CONTAINING FUNCTIONAL GROUPS PER MOLECULE; COATINGS, INKS, ADHESIVES NOF CORPORATION (JP) 1999-11-30 US disclosed
WO-1999012986-A1 POLYMER COMPOSITION INEOS ACRYLICS UK LIMITED (GB) 1999-03-18 WO disclosed