Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105422 | 0.95 | NPC1 (0.35) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7111654 | 0.91 | NPC1 (0.36) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7109460 | 0.88 | GCGR (0.38) | NPC1RAB9ASMN1; SMN2TLR8DHFR | |
| SCHEMBL7109432 | 0.87 | KDM4E (0.41) | RAB9ALMNATP53SMN1; SMN2TLR8 | |
| SCHEMBL7111520 | 0.86 | TLR8 (0.38) | NPC1RAB9ASMN1; SMN2TLR8DHFR | |
| SCHEMBL7111531 | 0.86 | KDM4E (0.40) | RAB9ALMNATP53SMN1; SMN2TLR8 | |
| SCHEMBL7108900 | 0.86 | KDM4E (0.40) | RAB9ALMNATP53SMN1; SMN2TLR8 | |
| SCHEMBL7110767 | 0.86 | KDM4E (0.38) | RAB9ALMNATP53SMN1; SMN2TLR8 | |
| SCHEMBL7106420 | 0.86 | NPC1 (0.38) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7111529 | 0.84 | GCGR (0.35) | TLR8DHFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053263-B1 | CATALYST SYSTEM | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | claimed |